You are probably hearing digital distortion. It happens when the settings add up to a too high level of amplification. The formula is:
Volume + max(Bass, Treble) + Loudness <= 0dB
(Unfortunately, the volume is in percent and not dB, so it's not easy for the user to calculate.)
This means that you must turn down the volume if you increase the bass/treble/loudness to avoid distortion. FYI, 0dB volume is 93%.