EQ settings are really subjective...what sounds good for me may sound terrible for you. What you could do is go to the e4 website and get the frequency response data for the headphones, and then try to "invert" the response using the eq in each band. This will get you close to a flat response, which is what you want if you want to hear what the audio engineer/band intended for you to hear...
I also have some e4's and love 'em! haven't tweaked my eq yet, as I am still learning how to use rb...
good luck!